S-Isomer Ketamine

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Description

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Ketamine, sold under the brand names Spravato (for depression) and Keta (for anesthesia) among others,
is the S(+) enantiomer of ketamine. It is a dissociative hallucinogen drug used as a general anesthetic and as an
antidepressant for treatment of depression. Ketamine is the active enantiomer of ketamine in terms of NMDA receptor
antagonism and is more potent than racemic ketamine. It is specifically used as a therapy for treatment-resistant depression (TRD) and for major depressive disorder (MDD)
with co-occurring suicidal ideation or behavior. Its efficacy for depression is modest and similar to that of
other antidepressants. Ketamine is not used by infusion into a vein for depression as it is only FDA-approved
in the form of a nasal spray under direct medical supervision for this indication (the parent compound ketamine is most
often administered intravenously).

Ketamine is a cyclohexanone-derived general anesthetic and NMDA receptor antagonist with analgesic
and hallucinogenic properties